HETLIOZ is indicated for the treatment of Non-24-Hour Sleep-Wake Disorder (Non-24). 2 DOSAGE AND ADMINISTRATION

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_______________ WARNINGS AND PRECAUTIONS_______________ May cause somnolence: After taking HETLIOZ, patients should limit their activity to preparing for going to bed, because HETLIOZ can impair the performance of activities requiring complete mental alertness (5.1) ___________________ ADVERSE REACTIONS ___________________ The most common adverse reactions (incidence >5% and at least twice as high on HETLIOZ than on placebo) were headache, increased alanine aminotransferase, nightmares or unusual dreams, and upper respiratory or urinary tract infection (6.1)

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تاریخ انتشار 2014